Anti-wrinkle treatment with ‘Botox’ is the most popular cosmetic treatment in the world, and we can see why! It is used in anti-aging treatment to reduce the muscles of facial expression, which softens and prevents unwanted lines and wrinkles. They are most commonly used in the upper third of the face, with the 3 most popular areas being the frown lines, the forehead lines and the crow’s feet around the eyes.